Bioactive Small Molecules
Medchemexpress LLC HY-134957 5mg , VT107 CAS:2417718-63-7 Purity:>98%
HY-134957 5mg VT107 CAS: 2417718-63-7 VT-107, as an analogous to VT104, is an orally active and potent pan-TEAD auto-palmitoylation inhibitor. VT-107 can be used for the research of cancer. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Nx-1607 | 2573775-59-2 | 99.9% | 537.62 | C30H34F3N5O | 5 MG
NX-1607 is a first-in-class, orally bioavailable small-molecule inhibitor of the E3 ubiquitin ligase Cbl-b. It exhibits sub-nanomolar potency (IC50 < 1 nM) and is used in preclinical and clinical immuno-oncology research to enhance T-cell activation, reduce exhaustion, and increase antigen recall and cytokine production. Supplied for laboratory research use only.
- Potent sub-nanomolar inhibitory activity against Cbl-b.
- Enhances T-cell activation and antigen recall.
- Reduces T-cell exhaustion and increases cytokine production.
- Orally bioavailable small molecule suitable for in vivo studies.
- High purity solid with white to off-white appearance.
- Stable when stored sealed; follow recommended storage conditions.
- Supplied in small-scale packaging for research applications.
Medchemexpress LLC Dota-(t-butyl)3-peg5-azide | 00-00-0 | 99.7% | 861.08 g/mol | C40H76N8O12 | 5 MG
DOTA-(t-butyl)3-PEG5-azide is a PEG-based linker containing a protected DOTA chelator and a terminal azide group. It is designed for bioconjugation and linker synthesis, enabling efficient coupling to alkyne-bearing partners via copper-catalyzed or strain-promoted azide-alkyne cycloaddition. The reagent offers a flexible spacer and high purity for reproducible coupling reactions.
Medchemexpress LLC Lomitapide mesylate | 202914-84-9 | MFCD19443682 | 99.6% | 789.83 g/mol | C40H41F6N3O5S | 5 MG
Lomitapide mesylate is the mesylate salt form of lomitapide, a potent inhibitor of microsomal triglyceride transfer protein (MTP). It is supplied as a high-purity analytical standard for in vitro and biochemical research, with a reported IC50 of 8 nM. The product is intended for analytical and research applications where a stable, well-characterized MTP inhibitor is required.
- Potent MTP inhibitor with reported IC50 of 8 nM.
- High purity suitable for analytical and in vitro research.
- Provided as a stable solid, convenient for formulation and storage.
- Molecular formula C40H41F6N3O5S and molecular weight ≈ 789.8 g/mol.
- Available in small-scale quantities for analytical use.
Selleck Chemical LLC Ethopabate S3707-25mg
Ethopabate (ETP Ethyl pabate) is a coccidiostat that is frequently used to prevent and treat coccidiosis in chickens
Medchemexpress LLC Biotin-labeled agatolimod sodium | 00-00-0 | 97.2% | 8,632.40 Da | 5 MG
Biotin-labeled agatolimod sodium is a biotin-conjugated class B CpG oligodeoxynucleotide that acts as a TLR9 agonist. Supplied as a white to off-white solid, it is designed for research use to evaluate cellular uptake and localization of CpG ODNs using biotin detection systems and light microscopy.
- Biotin tag enables detection with standard streptavidin/biotin systems.
- Class B CpG sequence activates TLR9 in human-relevant assays.
- High reported purity supports reproducible experimental results.
- Solid form simplifies storage and handling for bench workflows.
- Available in small research-scale quantities for assay development.
Medchemexpress LLC hGPR91 antagonist 1 | 1314796-00-3 | 99.9% | 529.53 g/mol | C31H23F4N3O | 10MG
hGPR91 antagonist 1 (Compound 4c) is a potent and selective antagonist of the human GPR91 (succinate receptor) with a reported IC50 of 7 nM. The compound is supplied as a white to off-white solid with high reported purity and is intended for research use in GPCR pharmacology, signaling assays, and in vitro profiling. Recommended storage conditions are provided for powder and solution forms to preserve stability and shelf life.
- Potent antagonist of human GPR91 (IC50 7 nM).
- High reported purity (99.94%).
- White to off-white solid suitable for analytical and biological studies.
- Multiple package sizes available, including small milligram quantities for screening.
- Recommended storage: powder at -20°C (long term) or 4°C (shorter term); in solvent at -80°C for extended storage.
- Provided structural identifiers for cheminformatics and synthesis reference.
Medchemexpress LLC HY-10518 50mg Medchemexpress, BMS-345541 BMS-345541 hydrochloride CAS:547757-23-3 Purity:98%
Medchemexpress,HY-10518 50mg BMS-345541 BMS-345541 hydrochloride CAS:547757-23-3 Formula:C14H18ClN5 BMS-345541 is a selective inhibitor of the catalytic subunits of IKK (IKK-2 IC50=0.3 μM, IKK-1 IC50=4 μM). BMS-345541 binds at an allosteric site of IKK. Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Cayman Chemical 2-OxoadIpIc AcId 5mg
An intermediate in the catabolism of L-tryptophan, L-lysine, and hydroxylysine; urinary excretion is increased in patients with α-ketoadipic aciduria
Medchemexpress LLC (S,S)-BMS-984923 | 1375752-77-4 | 98.8% | 374.8 g/mol | C22H15ClN2O2 | 5 MG
(S,S)-BMS-984923 is the (S,S)-enantiomer of an mGluR5 silent allosteric modulator provided as a research reagent. It is described as a less active enantiomer versus the parent compound and is intended for in vitro research applications as a solid powder.
eMolecules 470-37-1 | Medchem Express | Cinobufagin | 5mg | 446275045 | HY-N0421 | MFCD00056825 | 442.552 | C26H34O6
Ambeed | 3-(1H-Pyrazol-1-yl)propane-12-diol | 1g | 525007879 | A114151 | 98484-49-2 | MFCD11846459 | 142.158 | C6H10N2O2
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool<|a>
Medchemexpress LLC Erk5-in-1 | 1234479-76-5 | >98.0% | 459.54 g/mol | C25H29N7O2 | 5 MG
ERK5-IN-1 is a small-molecule kinase inhibitor selective for ERK5 (MAPK7) with reported biochemical potency (ERK5 IC50 = 87 ± 7 nM) and activity against LRRK2[G2019S] (IC50 = 26 nM). It is intended for research use in biochemical and cell signaling studies of the MAPK/ERK pathway.
- Potent ERK5 inhibition (IC50 ≈ 87 nM).
- Also inhibits LRRK2[G2019S] (IC50 ≈ 26 nM).
- Suitable for biochemical kinase assays and cell signaling studies.
- Available as solid powder and as DMSO solution formats for convenience.
- Molecular formula C25H29N7O2; molecular weight 459.54 g/mol.
- For research use only; not for human or veterinary use.
Medchemexpress LLC Biotin-PEG8-NHS ester | 2143968-03-8 | 99.9% | 764.88 | C33H56N4O14S | 5 MG
Biotin-PEG8-NHS ester is a biotinylation reagent composed of a biotin group linked via an 8-unit polyethylene glycol spacer to an N-hydroxysuccinimide (NHS) ester. The NHS ester reacts selectively with primary amines to form stable amide bonds, making this compound suitable for conjugation to peptides, proteins, and other amine-containing molecules for labeling, affinity capture, and linker applications in degraders research.
- High purity (99.9%).
- PEG8 spacer improves solubility and reduces steric hindrance.
- Reactive NHS ester enables efficient amine coupling.
- Suitable for protein labeling and affinity purification.
- Available in small research-scale pack sizes for convenience.
Medchemexpress LLC ODN 1826 sodium | 00-00-0 | 99.5% | 6364.1 (free acid) | 5 MG
ODN 1826 sodium is a class B CpG oligodeoxynucleotide that functions as a TLR9 agonist for research applications. It stimulates innate immune responses, inducing nitric oxide (NO) and iNOS production, and can enhance apoptosis and antitumor immune surveillance in preclinical studies. Supplied as a sodium salt with a defined phosphorothioate-modified sequence and high purity, it is intended for research use only.
- Acts as a TLR9 agonist to stimulate innate immunity.
- Induces nitric oxide and iNOS production.
- Enhances apoptosis in responsive cells.
- Shows reported antitumor activity in preclinical models.
- Provided as a sodium salt, solid, white to off-white.
- High purity (99.5%).
- Store dry, sealed, away from moisture; in solvent: -80°C up to 6 months, -20°C up to 1 month.
- For research use only.
Medchemexpress LLC Biotin-PEG6-NHS ester | 2055045-04-8 | MFCD22056308 | 98.0% | 676.78 g/mol | C29H48N4O12S | 5 MG
Biotin-PEG6-NHS ester is an amine-reactive biotinylation reagent composed of a PEG6 spacer terminated with an N-hydroxysuccinimide (NHS) ester. It couples to primary amines to form stable amide bonds, enabling attachment of a biotin tag for affinity capture, detection, or incorporation into linker constructs used in chemical biology and PROTAC research.